What is done in a cross-linking operation? Is this operation really effective?
The cornea is made of a network of collagen fibers. In this disease interlinking connections between the collagen fibers become week due to which the corneal thickness decreases and the cornea is weakened.
In this treatment, the collagen fibers are activated and their linkages between each other are potentiated and their cross-links are fastened together with each other. A chemical named riboflavin is activated with a special type of ultraviolet radiation, as a results the fibers of the collagen come closer to each other again, and thickness of cornea increases. This process is called cross-linking. This operation is also called CXR or CR3 operation.
As this chemical and radiation machine are still expensive so the operation is much expensive and is being performed at very few places.
The pictures below show the different stages of this operation
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